In our new study on bioabsobable implants, just published in the Journal of Biomedical Materials Research A (Vol. 102, Issue 3, pp. 341-349), we present an in vitro – in vivo biocorrosion correlation for pure magnesium. The studies rely on experimental corrosion rates in the murine artery and in DMEM immersion testing. This is, as far as we know, the first correlation of this kind. Understanding of the in vitro – in vivo biocorrosion correlation for biodegradable materials could reduce the number of animal studies in a future. Predictions of in vivo stent biodegradation is thus highly significant and innovative. The studies described in the paper were led by Patrick Bowen.
New Publication on Biodegradation of Mg
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