Our collaborator from Brock University in Canada, Prof. Jeffrey A. Stuart, investigated biological effects of Zn-based stent materials. His research team identified mitochondria as an important target of zinc that is differently affected in the vascular endothelial and smooth muscle cells. This new finding is important for better understanding how zinc-based implants affect tissue homeostasis in vivo. The summary of this study is published in the Biomaterials and Biosystems journal in the article entitled Bioabsorbable Metal Zinc Differentially Affects Mitochondria in Vascular Endothelial and Smooth Muscle Cells. The paper is co-authored by Prof. Jeremy Goldman and Prof. Jaroslaw Drelich.
Biological effects of Zn
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